The Strategy establishes reduction challenges for an initial list of persistent toxic substances targeted for virtual elimination: aldrin/dieldrin, benzo(a)pyrene, chlordane, DDT, hexachlorobenzene, alkyl-lead, mercury and compounds, mirex, octachlorostyrene, PCBs, dioxins and furans, and toxaphene. These substances have been associated with widespread, long-term adverse effects on wildlife in the Great Lakes, and, through their bioaccumulation, are of concern for human health. This is the first time specific reduction targets have been set jointly by the two countries.
http://www.epa.gov/grtlakes/bns/index.html
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